HUMIRA for Moderate to Severe Ulcerative Colitis (UC) in Adults
HUMIRA for Moderate to Severe Ulcerative Colitis (UC) in Adults
What is HUMIRA?
HUMIRA is a prescription medicine used to treat moderate to severe ulcerative colitis (UC) in adults and children 5 years of age and older. It is not known if HUMIRA is effective in people who stopped responding to or could not tolerate TNF-blocker medicines.
HUMIRA Results for Adult Ulcerative Colitis
REMISSION AT 8 WEEKS
In clinical studies, nearly 2x more patients achieved remission on HUMIRA at 8 weeks compared to placebo*
In one clinical study, 18.5% of patients with moderate to severe ulcerative colitis (UC) achieved remission as early as 8 weeks versus 9.2% on placebo. In a second study, 16.5% of patients achieved remission on HUMIRA at 8 weeks versus 9.3% on placebo.*
Remission at 1 year
As part of a second clinical trial, 17.3% of patients taking HUMIRA were in remission at 52 weeks
A controlled study of 494 patients included those who were new to a biologic as well as those who had taken a biologic treatment in the past. At week 52, 17.3% were in remission with HUMIRA compared to 8.5% taking placebo.*
Individual results may vary.
*A placebo is a substance that has no physical effect. In a clinical study, it is given to one group of patients, while the drug being tested is given to another group, then the results are compared.
Common side effects of HUMIRA
Common side effects of HUMIRA include injection site reactions (pain, redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA. Tell your doctor if you have any side effect that bothers you or that does not go away.
Read about the Important Safety Information for HUMIRA.
HUMIRA Dosing for Adult Ulcerative Colitis
Important: You must pay attention to your starting dose—it is different than your maintenance dose and is a critical part of taking HUMIRA as prescribed. Always follow your doctor’s instructions about when and how often to take HUMIRA.*
Starting dose
Starting doses are higher doses to help you quickly reach an effective concentration of medicine in your body and they are typically administered on Day 1 and Day 15 of your treatment with HUMIRA. An initial Day 1 dose is 160 mg (given in one day or split over two consecutive days) followed by 80 mg on Day 15.
Your first dose of HUMIRA must be given under the supervision of a health care professional. Make sure you have been shown how to inject HUMIRA before you do it yourself. Remember to keep your HUMIRA refrigerated in its original container until ready for use.
HUMIRA is given by an injection under the skin.
You should continue taking HUMIRA as directed by your doctor. Remember, HUMIRA is a treatment, not a cure. Your doctor can tell you if and when you should stop taking HUMIRA.
For more information, refer to the Patient Instructions for Use and the Medication Guide located inside the HUMIRA carton, and within the Full Prescribing Information. If you experience any adverse reactions or discomfort when taking HUMIRA, discuss them with your doctor right away.
*Refer to the Patient Instructions for Use to learn about the HUMIRA Pen and prefilled syringe.
Start with support that’s designed around you
HUMIRA Complete gives you access to potential savings, injection training guides, and other helpful resources. Plus, you’re a phone call away from getting help with insurance coverage support.
How does HUMIRA work?
The protein TNF-alpha is believed to be part of your body’s natural processes involved in creating inflammation, and in some cases, excess inflammation. When used as prescribed, HUMIRA targets and blocks TNF-alpha, which can help reduce excess inflammation associated with moderate to severe UC.
Explore a different ulcerative colitis treatment option.
Learn about a once-daily pill for people with moderate to severe ulcerative colitis who have already tried a TNF blocker like HUMIRA.